Insulin initiation refers to the process of starting insulin therapy in individuals with diabetes who have not been previously prescribed insulin. This decision is typically made when blood glucose levels are not adequately controlled through other treatment options such as oral medications or lifestyle changes. Insulin initiation involves determining the appropriate type of insulin, dosage, and timing of administration based on individual factors such as age, weight, blood glucose levels, and lifestyle. It is essential to closely monitor the individual's blood glucose levels and make adjustments as needed to achieve target goals and prevent complications of diabetes. Research in the area of insulin initiation focuses on improving the effectiveness and safety of insulin therapy, individualizing treatment approaches, and exploring new insulin formulations or delivery methods. This research aims to optimize glycemic control, reduce the risk of hypoglycemia, and improve the quality of life for individuals requiring insulin therapy.